A new study conducted by researchers at Harvard Medical School reveals that by pairing nanoparticle-delivered cancer therapies with radiation, it is possible to make it six times more effective.
Injecting nanoparticles, a very small molecule of medicine, near tumors that are being treated with high-energy radiation is how the process works. The high-energy radiation triggers the patient’s immune cells to work in conjunction with the nanoparticles, causing the blood vessels embedded in the tumor to leak the life-saving medicine directly into the diseased tissue.Miles Miller, lead author and researcher at Harvard Medical School, said the study highlights the significance of utilizing nanomedicine to better target malignant cells, a technique with limited success until now.
“Rather than focusing on the nanoparticles themselves, we used in vivo microscopy to discover how to rewire the structure of the tumor itself to more efficiently accumulate a variety of nanomedicines already in clinical use,” Miller said.
The researcher note that the next step is to verify the findings in a full clinical trial, which should progress rather quickly, since the Food and Drug Administration (FDA), has already approved the medicines in question.